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Melatonin modulates Nrf2 activity to protect porcine pre‐pubertal Sertoli cells from the abnormal H(2)O(2) generation and reductive stress effects of cadmium

Melatonin (MLT) is a cytoprotective agent holding potential to prevent cadmium (Cd) toxicity and its impact in testicular function and fertility. In this study, we explored such potential in porcine pre‐pubertal Sertoli cells (SCs). Cd toxicity resulted in impaired SC viability and function, abnorma...

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Detalles Bibliográficos
Autores principales: Bartolini, Desirée, Arato, Iva, Mancuso, Francesca, Giustarini, Daniela, Bellucci, Catia, Vacca, Carmine, Aglietti, Maria Chiara, Stabile, Anna Maria, Rossi, Ranieri, Cruciani, Gabriele, Rende, Mario, Calafiore, Riccardo, Luca, Giovanni, Galli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539639/
https://www.ncbi.nlm.nih.gov/pubmed/35524288
http://dx.doi.org/10.1111/jpi.12806