Dissociating motor impairment from five-choice serial reaction time task performance in a mouse model of Angelman syndrome

Angelman syndrome (AS) is a single-gene neurodevelopmental disorder associated with cognitive and motor impairment, seizures, lack of speech, and disrupted sleep. AS is caused by loss-of-function mutations in the UBE3A gene, and approaches to reinstate functional UBE3A are currently in clinical tria...

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Detalles Bibliográficos
Autores principales: Negrón-Moreno, Paola N., Diep, David T., Guoynes, Caleigh D., Sidorov, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Behavioral Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539753/
https://www.ncbi.nlm.nih.gov/pubmed/36212189
http://dx.doi.org/10.3389/fnbeh.2022.968159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539753/
https://www.ncbi.nlm.nih.gov/pubmed/36212189
http://dx.doi.org/10.3389/fnbeh.2022.968159

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