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Dissociating motor impairment from five-choice serial reaction time task performance in a mouse model of Angelman syndrome
Angelman syndrome (AS) is a single-gene neurodevelopmental disorder associated with cognitive and motor impairment, seizures, lack of speech, and disrupted sleep. AS is caused by loss-of-function mutations in the UBE3A gene, and approaches to reinstate functional UBE3A are currently in clinical tria...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539753/ https://www.ncbi.nlm.nih.gov/pubmed/36212189 http://dx.doi.org/10.3389/fnbeh.2022.968159 |