MOF negatively regulates estrogen receptor α signaling via CUL4B-mediated protein degradation in breast cancer

Estrogen receptor α (ERα) is the dominant tumorigenesis driver in breast cancer (BC), and ERα-positive BC (ERα+ BC) accounts for more than two-thirds of BC cases. MOF (males absent on the first) is a highly conserved histone acetyltransferase that acetylates lysine 16 of histone H4 (H4K16) and sever...

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Detalles Bibliográficos
Autores principales: Zhang, Xu, Yang, Yang, Li, Danyang, Wu, Zhen, Liu, Haoyu, Zhao, Ziyan, Zhu, Hongying, Xie, Fei, Li, Xiangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539768/
https://www.ncbi.nlm.nih.gov/pubmed/36212422
http://dx.doi.org/10.3389/fonc.2022.868866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539768/
https://www.ncbi.nlm.nih.gov/pubmed/36212422
http://dx.doi.org/10.3389/fonc.2022.868866

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