Efficacy of erlotinib in NSCLC harboring rare EGFR extracellular domain mutation (T263P) and common mutations: Case report and literature review

The epidermal growth factor receptor (EGFR) typically contains an extracellular domain (ECD), a transmembrane (TM) domain, and an intracellular kinase (KD) domain. ECD mutations of EGFR in NSCLC may affect its normal function and intrinsic resistance to tyrosine kinase inhibitors (TKIs) and the effe...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Wang, Yong, Zhang, Xinwei, Fang, Chen, Qian, Xiaoying, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539819/
https://www.ncbi.nlm.nih.gov/pubmed/36212397
http://dx.doi.org/10.3389/fonc.2022.954026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539819/
https://www.ncbi.nlm.nih.gov/pubmed/36212397
http://dx.doi.org/10.3389/fonc.2022.954026

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