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Genomic profiling identifies genes and pathways dysregulated by HEY1–NCOA2 fusion and shines a light on mesenchymal chondrosarcoma tumorigenesis

Mesenchymal chondrosarcoma is a rare, high‐grade, primitive mesenchymal tumor. It accounts for around 2–10% of all chondrosarcomas and mainly affects adolescents and young adults. We previously described the HEY1–NCOA2 as a recurrent gene fusion in mesenchymal chondrosarcoma, an important breakthrou...

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Detalles Bibliográficos
Autores principales: Qi, Wenqing, Rosikiewicz, Wojciech, Yin, Zhaohong, Xu, Beisi, Jiang, Huihong, Wan, Shibiao, Fan, Yiping, Wu, Gang, Wang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539848/
https://www.ncbi.nlm.nih.gov/pubmed/35342947
http://dx.doi.org/10.1002/path.5899