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Methyltransferases: Functions and Applications

In this review the current state‐of‐the‐art of S‐adenosylmethionine (SAM)‐dependent methyltransferases and SAM are evaluated. Their structural classification and diversity is introduced and key mechanistic aspects presented which are then detailed further. Then, catalytic SAM as a target for drugs,...

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Detalles Bibliográficos
Autores principales: Abdelraheem, Eman, Thair, Benjamin, Varela, Romina Fernández, Jockmann, Emely, Popadić, Désirée, Hailes, Helen C., Ward, John M., Iribarren, Adolfo M., Lewkowicz, Elizabeth S., Andexer, Jennifer N., Hagedoorn, Peter‐Leon, Hanefeld, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539859/
https://www.ncbi.nlm.nih.gov/pubmed/35691829
http://dx.doi.org/10.1002/cbic.202200212