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Maternal siRNA silencing of placental SAA2 mitigates preterm birth following intrauterine inflammation

The placental inflammatory processes induced maternally result in preterm birth (PTB). Serum amyloid A (SAA) is a well-known biomarker of inflammation. The objective of this study was to investigate whether murine placental SAA isoforms (SAA1–4) participate in the mechanism of spontaneous PTB and wh...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Liu, Jin, Liu, Anguo, Yin, Hillary, Burd, Irina, Lei, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539923/
https://www.ncbi.nlm.nih.gov/pubmed/36211368
http://dx.doi.org/10.3389/fimmu.2022.902096