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NURR1‐deficient mice have age‐ and sex‐specific behavioral phenotypes

The transcription factor NURR1 is essential to the generation and maintenance of midbrain dopaminergic (mDA) neurons and its deregulation is involved in the development of dopamine (DA)‐associated brain disorders, such as Parkinson's disease (PD). The old male NURR1 heterozygous knockout (NURR1...

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Detalles Bibliográficos
Autores principales: Montarolo, Francesca, Martire, Serena, Chiara, Francesco, Allegra, Sarah, De Francia, Silvia, Hoxha, Eriola, Tempia, Filippo, Capobianco, Marco Alfonso, Bertolotto, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539971/
https://www.ncbi.nlm.nih.gov/pubmed/35593070
http://dx.doi.org/10.1002/jnr.25067