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DJ‐1 is not a deglycase and makes a modest contribution to cellular defense against methylglyoxal damage in neurons

Human DJ‐1 is a cytoprotective protein whose absence causes Parkinson's disease and is also associated with other diseases. DJ‐1 has an established role as a redox‐regulated protein that defends against oxidative stress and mitochondrial dysfunction. Multiple studies have suggested that DJ‐1 is...

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Detalles Bibliográficos
Autores principales: Mazza, Melissa Conti, Shuck, Sarah C., Lin, Jiusheng, Moxley, Michael A., Termini, John, Cookson, Mark R., Wilson, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539984/
https://www.ncbi.nlm.nih.gov/pubmed/35713360
http://dx.doi.org/10.1111/jnc.15656