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UV‐induced DNA Damage in Skin is Reduced by CaSR Inhibition

The epidermis maintains a cellular calcium gradient that supports keratinocyte differentiation from its basal layers (low) to outer layers (high) leading to the development of the stratum corneum, which resists penetration of UV radiation. The calcium‐sensing receptor (CaSR) expressed in keratinocyt...

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Detalles Bibliográficos
Autores principales: Yang, Chen, Rybchyn, Mark Stephen, De Silva, Warusavithana Gunawardena Manori, Matthews, Jim, Holland, Andrew J. A., Conigrave, Arthur David, Mason, Rebecca Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540002/
https://www.ncbi.nlm.nih.gov/pubmed/35288938
http://dx.doi.org/10.1111/php.13615