Cargando…

UV‐induced DNA Damage in Skin is Reduced by CaSR Inhibition

The epidermis maintains a cellular calcium gradient that supports keratinocyte differentiation from its basal layers (low) to outer layers (high) leading to the development of the stratum corneum, which resists penetration of UV radiation. The calcium‐sensing receptor (CaSR) expressed in keratinocyt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Chen, Rybchyn, Mark Stephen, De Silva, Warusavithana Gunawardena Manori, Matthews, Jim, Holland, Andrew J. A., Conigrave, Arthur David, Mason, Rebecca Sara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540002/ https://www.ncbi.nlm.nih.gov/pubmed/35288938 http://dx.doi.org/10.1111/php.13615

Ejemplares similares

The CaSR Modulator NPS-2143 Reduced UV-Induced DNA Damage in Skh:hr1 Hairless Mice but Minimally Inhibited Skin Tumours
por: Yang, Chen, et al.
Publicado: (2023)

The mTORC2 Regulator Homer1 Modulates Protein Levels and Sub-Cellular Localization of the CaSR in Osteoblast-Lineage Cells
por: Rybchyn, Mark S., et al.
Publicado: (2021)

The Over-Irradiation Metabolite Derivative, 24-Hydroxylumister-ol(3), Reduces UV-Induced Damage in Skin
por: De Silva, Warusavithana Gunawardena Manori, et al.
Publicado: (2023)

Evidence for Involvement of Nonclassical Pathways in the Protection From UV‐Induced DNA Damage by Vitamin D–Related Compounds
por: De Silva, Warusavithana Gunawardena Manori, et al.
Publicado: (2021)

Physiological studies in heterozygous calcium sensing receptor (CaSR) gene-ablated mice confirm that the CaSR regulates calcitonin release in vivo
por: Fudge, Neva J, et al.
Publicado: (2004)

OR11-003 - The NLRP3 inflammasome is regulated by CaSR
por: Chae, JJ, et al.
Publicado: (2013)

ERK signaling mediates CaSR-promoted axon growth
por: Vizard, Thomas N., et al.
Publicado: (2015)

Exosomes Released from CaSR-Stimulated PMNs Reduce Ischaemia/Reperfusion Injury
por: Zhai, Tai-yu, et al.
Publicado: (2021)

Ca(2+)/Sr(2+) Selectivity in Calcium-Sensing Receptor (CaSR): Implications for Strontium’s Anti-Osteoporosis Effect
por: Cheshmedzhieva, Diana, et al.
Publicado: (2021)

Calcium-sensing receptor (CaSR) as a novel target for ischemic neuroprotection
por: Kim, Jong Youl, et al.
Publicado: (2014)

An Unusual Case of Meningioma Showing Increased CaSR Expression with Parathyroid Carcinoma
por: Yoo, Jin Sae, et al.
Publicado: (2018)

Synthesis and characterization of CaSr-Metal Organic Frameworks for biodegradable orthopedic applications
por: Joseph, Naomi, et al.
Publicado: (2019)

CaSR Induces Osteoclast Differentiation and Promotes Bone Metastasis in Lung Adenocarcinoma
por: Liu, Lian, et al.
Publicado: (2020)

Calcium-Sensing Receptor (CaSR)-Mediated Intracellular Communication in Cardiovascular Diseases
por: Chu, Hezhen, et al.
Publicado: (2022)

Phenylalanine promotes alveolar macrophage pyroptosis via the activation of CaSR in ARDS
por: Tang, Yiding, et al.
Publicado: (2023)

SAT-350 A Tale of Two Mutations: Familial Hypocalciuric Hypercalcemia Caused by a Novel CaSR Start Codon Mutation Found in the Setting of a CaSR Hypercalciuric Variant
por: Bandaru, Sindhura, et al.
Publicado: (2020)

SUN-266 Protein Induced Pancreatic Hormone Secretion Is Modulated by Vagal CaSR
por: Norton, Mariana, et al.
Publicado: (2020)

Calcium-Sensing Receptor (CaSR), Its Impact on Inflammation and the Consequences on Cardiovascular Health
por: Sundararaman, Sai Sahana, et al.
Publicado: (2021)

Effects of Sodium Ferulate on Cardiac Hypertrophy Are via the CaSR-Mediated Signaling Pathway
por: Chen, Panpan, et al.
Publicado: (2021)

Aberrant upregulation of CaSR promotes pathological new bone formation in ankylosing spondylitis
por: Li, Xiang, et al.
Publicado: (2020)

Oral expressions and functional analyses of the extracellular calcium-sensing receptor (CaSR) in chicken
por: Omori, Hikaru, et al.
Publicado: (2022)

Calcium-sensing receptor (CaSR) promotes development of bone metastasis in renal cell carcinoma
por: Frees, Sebastian, et al.
Publicado: (2018)

De novo a novel variant of CaSR gene in a neonate with congenital hypoparathyroidism
por: Moon, Jung-Eun, et al.
Publicado: (2018)

Genetic polymorphism (rs6776158) in CaSR gene is associated with risk of nephrolithiasis in Chinese population
por: Zhou, Hai, et al.
Publicado: (2018)

The CaSR in Pathogenesis of Breast Cancer: A New Target for Early Stage Bone Metastases
por: Das, Souvik, et al.
Publicado: (2020)

OR07-06 The Roles of GNAQ and GNA11 in Calcium-Sensing Receptor (CaSR) Signalling
por: Gluck, Anna K, et al.
Publicado: (2020)

A novel CaSR mutation presenting as a severe case of neonatal familial hypocalciuric hypercalcemia
por: Tonyushkina, Ksenia N, et al.
Publicado: (2012)

Calcimimetic acts on enteric neuronal CaSR to reverse cholera toxin-induced intestinal electrolyte secretion
por: Tang, Lieqi, et al.
Publicado: (2018)

Genetic polymorphism (rs6776158) in CaSR gene is associated with risk of nephrolithiasis in Chinese population: Erratum
Publicado: (2018)

CaSR-Mediated hBMSCs Activity Modulation: Additional Coupling Mechanism in Bone Remodeling Compartment
por: Cho, Hyunji, et al.
Publicado: (2020)

Successful prednisolone or calcimimetic treatment of acquired hypocalciuric hypercalcemia caused by biased allosteric CaSR autoantibodies
por: Makita, Noriko, et al.
Publicado: (2022)

Familial hypocalciuric hypercalcemia caused by homozygous CaSR gene mutation: A case report of a family
por: Wang, Feifei, et al.
Publicado: (2020)

The Calcium-Sensing Receptor (CaSR) Variants at rs1801725 Increase the Risk of Developing Secondary Malignant Cancers
por: Beasley, Heather K, et al.
Publicado: (2021)

An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damage
por: Agrez, Michael, et al.
Publicado: (2023)

PTH1R-CaSR Cross Talk: New Treatment Options for Breast Cancer Osteolytic Bone Metastases
por: Yang, Yanmei, et al.
Publicado: (2018)

MCPIP1-induced autophagy mediates ischemia/reperfusion injury in endothelial cells via HMGB1 and CaSR
por: Xie, Xiaolong, et al.
Publicado: (2018)

Case report: acute clinical presentation and neonatal management of primary hyperparathyroidism due to a novel CaSR mutation
por: Capozza, Manuela, et al.
Publicado: (2018)

Tojapride prevents CaSR‐mediated NLRP3 inflammasome activation in oesophageal epithelium irritated by acidic bile salts
por: Yin, Xiao‐Lan, et al.
Publicado: (2019)

Fucoidan from Undaria pinnatifida Ameliorates Epidermal Barrier Disruption via Keratinocyte Differentiation and CaSR Level Regulation
por: Chen, Yu, et al.
Publicado: (2019)

Autosomal Dominant Hypocalcemia With Atypical Urine Findings Accompanied by Novel CaSR Gene Mutation and VitD Deficiency
por: Tsuji, Tomoya, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_k3reej81umr0m2j59jmu7d7mq6