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Quantitative mapping of force–pCa curves to whole‐heart contraction and relaxation

ABSTRACT: The force–pCa (F–pCa) curve is used to characterize steady‐state contractile properties of cardiac muscle cells in different physiological, pathological and pharmacological conditions. This provides a reduced preparation in which to isolate sarcomere mechanisms. However, it is unclear how...

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Detalles Bibliográficos
Autores principales: Longobardi, Stefano, Sher, Anna, Niederer, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540007/
https://www.ncbi.nlm.nih.gov/pubmed/35737959
http://dx.doi.org/10.1113/JP283352