A regulatory network of Sox and Six transcription factors initiate a cell fate transformation during hearing regeneration in adult zebrafish

Using adult zebrafish inner ears as a model for sensorineural regeneration, we ablated the mechanosensory receptors and characterized the single-cell epigenome and transcriptome at consecutive time points during hair cell regeneration. We utilized deep learning on the regeneration-induced open chrom...

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Detalles Bibliográficos
Autores principales: Jimenez, Erin, Slevin, Claire C., Song, Wei, Chen, Zelin, Frederickson, Stephen C., Gildea, Derek, Wu, Weiwei, Elkahloun, Abdel G., Ovcharenko, Ivan, Burgess, Shawn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540346/
https://www.ncbi.nlm.nih.gov/pubmed/36212030
http://dx.doi.org/10.1016/j.xgen.2022.100170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540346/
https://www.ncbi.nlm.nih.gov/pubmed/36212030
http://dx.doi.org/10.1016/j.xgen.2022.100170

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