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HERVs characterize normal and leukemia stem cells and represent a source of shared epitopes for cancer immunotherapy

Human endogenous retroviruses (HERVs) represent 8% of the human genome. The expression of HERVs and their immune impact have not been extensively studied in Acute Myeloid Leukemia (AML). In this study, we used a reference of 14 968 HERV functional units to provide a thorough analysis of HERV express...

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Detalles Bibliográficos
Autores principales: Alcazer, Vincent, Bonaventura, Paola, Tonon, Laurie, Michel, Emilie, Mutez, Virginie, Fabres, Clémentine, Chuvin, Nicolas, Boulos, Rasha, Estornes, Yann, Maguer‐Satta, Véronique, Geistlich, Kevin, Viari, Alain, Metzeler, Klaus H., Hiddemann, Wolfgang, Batch, Aarif M. N., Herold, Tobias, Caux, Christophe, Depil, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540360/
https://www.ncbi.nlm.nih.gov/pubmed/35759575
http://dx.doi.org/10.1002/ajh.26647