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Cilia-related gene signature in the nasal mucosa correlates with disease severity and outcomes in critical respiratory syncytial virus bronchiolitis

BACKGROUND: Respiratory syncytial virus (RSV) can cause life-threatening respiratory failure in infants. We sought to characterize the local host response to RSV infection in the nasal mucosa of infants with critical bronchiolitis and to identify early admission gene signatures associated with clini...

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Detalles Bibliográficos
Autores principales: Koch, Clarissa M., Prigge, Andrew D., Setar, Leah, Anekalla, Kishore R., Do-Umehara, Hahn Chi, Abdala-Valencia, Hiam, Politanska, Yuliya, Shukla, Avani, Chavez, Jairo, Hahn, Grant R., Coates, Bria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540395/
https://www.ncbi.nlm.nih.gov/pubmed/36211387
http://dx.doi.org/10.3389/fimmu.2022.924792