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Pathways linked to unresolved inflammation and airway remodelling characterize the transcriptome in two independent severe asthma cohorts

BACKGROUND AND OBJECTIVE: Severe asthma (SA) is a heterogeneous disease. Transcriptomic analysis contributes to the understanding of pathogenesis necessary for developing new therapies. We sought to identify and validate mechanistic pathways of SA across two independent cohorts. METHODS: Transcripto...

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Detalles Bibliográficos
Autores principales: Sánchez‐Ovando, Stephany, Pavlidis, Stelios, Kermani, Nazanin Zounemat, Baines, Katherine Joanne, Barker, Daniel, Gibson, Peter G., Wood, Lisa G., Adcock, Ian M., Chung, Kian Fan, Simpson, Jodie Louise, Wark, Peter A.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540453/
https://www.ncbi.nlm.nih.gov/pubmed/35673765
http://dx.doi.org/10.1111/resp.14302