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Pathways linked to unresolved inflammation and airway remodelling characterize the transcriptome in two independent severe asthma cohorts
BACKGROUND AND OBJECTIVE: Severe asthma (SA) is a heterogeneous disease. Transcriptomic analysis contributes to the understanding of pathogenesis necessary for developing new therapies. We sought to identify and validate mechanistic pathways of SA across two independent cohorts. METHODS: Transcripto...
Autores principales: | Sánchez‐Ovando, Stephany, Pavlidis, Stelios, Kermani, Nazanin Zounemat, Baines, Katherine Joanne, Barker, Daniel, Gibson, Peter G., Wood, Lisa G., Adcock, Ian M., Chung, Kian Fan, Simpson, Jodie Louise, Wark, Peter A.B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540453/ https://www.ncbi.nlm.nih.gov/pubmed/35673765 http://dx.doi.org/10.1111/resp.14302 |
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