Population Pharmacokinetics and Pharmacodynamics of the Therapeutic and Adverse Effects of Ketamine in Patients With Treatment‐Refractory Depression

We aimed to develop population pharmacokinetic/pharmacodynamic (PK/PD) models that can effectively describe ketamine and norketamine PK/PD relationships for Montgomery–Åsberg Depression Rating Scale (MADRS) scores, blood pressure (BP), and heart rate (HR) following i.v., s.c., and i.m. ketamine admi...

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Detalles Bibliográficos
Autores principales: Abuhelwa, Ahmad Y., Somogyi, Andrew A., Loo, Colleen K., Glue, Paul, Barratt, Daniel T., Foster, David J.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540482/
https://www.ncbi.nlm.nih.gov/pubmed/35560226
http://dx.doi.org/10.1002/cpt.2640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540482/
https://www.ncbi.nlm.nih.gov/pubmed/35560226
http://dx.doi.org/10.1002/cpt.2640

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