Ziritaxestat Drug–Drug Interaction with Oral Contraceptives: Role of SULT1E1 Inhibition

In vitro signals indicate that ziritaxestat is a weak cytochrome P450 (CYP) 3A4 inhibitor and inducer. Therefore, potential drug–drug interactions (DDIs) with oral contraceptives were examined at a time when ziritaxestat was under development for treatment of fibrotic diseases. This open‐label, cros...

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Detalles Bibliográficos
Autores principales: Helmer, Eric, Karimian, Negin, Van Assche, Karen, Seghers, Ineke, Le Tallec, Sandrine, Cherala, Ganesh, Scott, Graham, Namour, Florence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540497/
https://www.ncbi.nlm.nih.gov/pubmed/35713964
http://dx.doi.org/10.1002/cpt.2689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540497/
https://www.ncbi.nlm.nih.gov/pubmed/35713964
http://dx.doi.org/10.1002/cpt.2689

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