Novel iron chelator SK4 demonstrates cytotoxicity in a range of tumour derived cell lines

Iron is an essential micronutrient due to its involvement in many cellular processes including DNA replication and OXPHOS. Tumors overexpress iron metabolism linked proteins which allow for iron accumulation driving high levels of proliferation. Our group has designed novel iron chelator SK4 which t...

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Detalles Bibliográficos
Autores principales: Abdelaal, Gina, Carter, Andrew, Panayiotides, Mihalis I., Tetard, David, Veuger, Stephany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540520/
https://www.ncbi.nlm.nih.gov/pubmed/36213122
http://dx.doi.org/10.3389/fmolb.2022.1005092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540520/
https://www.ncbi.nlm.nih.gov/pubmed/36213122
http://dx.doi.org/10.3389/fmolb.2022.1005092

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