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Novel iron chelator SK4 demonstrates cytotoxicity in a range of tumour derived cell lines
Iron is an essential micronutrient due to its involvement in many cellular processes including DNA replication and OXPHOS. Tumors overexpress iron metabolism linked proteins which allow for iron accumulation driving high levels of proliferation. Our group has designed novel iron chelator SK4 which t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540520/ https://www.ncbi.nlm.nih.gov/pubmed/36213122 http://dx.doi.org/10.3389/fmolb.2022.1005092 |