Cargando…

NLRP3 inflammasome triggers interleukin‐37 release from human monocytes

IL‐37 is an anti‐inflammatory member of the IL‐1 family that dampens inflammation associated with many noncommunicable diseases. However, mechanisms of IL‐37 regulation remain understudied. We aimed to investigate the enzymatic cleavage of IL‐37 that potentiates extracellular signalling, as well as...

Descripción completa

Detalles Bibliográficos
Autores principales: Gritsenko, Anna, Díaz‐Pino, Rodrigo, López‐Castejón, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540663/
https://www.ncbi.nlm.nih.gov/pubmed/35429346
http://dx.doi.org/10.1002/eji.202149724