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Host transcriptional responses in nasal swabs identify potential SARS-CoV-2 infection in PCR negative patients

We analyzed RNA sequencing data from nasal swabs used for SARS-CoV-2 testing. 13% of 317 PCR-negative samples contained over 100 reads aligned to multiple regions of the SARS-CoV-2 genome. Differential gene expression analysis compares the host gene expression in potential false-negative (FN: PCR ne...

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Detalles Bibliográficos
Autores principales: Saravia-Butler, Amanda M., Schisler, Jonathan C., Taylor, Deanne, Beheshti, Afshin, Butler, Dan, Meydan, Cem, Foox, Jonathon, Hernandez, Kyle, Mozsary, Chris, Mason, Christopher E., Meller, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540688/
https://www.ncbi.nlm.nih.gov/pubmed/36246576
http://dx.doi.org/10.1016/j.isci.2022.105310