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Developing a translational murine‐to‐canine pathway for an IL‐2/agonist anti‐CD40 antibody cancer immunotherapy

Human and canine sarcomas are difficult to treat soft tissue malignancies with an urgent need for new improved therapeutic options. Local recurrence rates for humans are between 10%–30%, and 30%–40% develop metastases. Outcomes for dogs with sarcoma vary with grade but can be similar. Pet dogs share...

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Detalles Bibliográficos
Autores principales: Proksch, Stephen Francis, Matthysen, Clinton Petrus, Jardine, John E., Wyatt, Ken Mark, Finlay, Jessica Renee, Nelson, Delia Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540797/
https://www.ncbi.nlm.nih.gov/pubmed/35315197
http://dx.doi.org/10.1111/vco.12813