Successful use of empagliflozin to treat neutropenia in two G6PC3‐deficient children: Impact of a mutation in SGLT5

Neutropenia and neutrophil dysfunction found in deficiencies in G6PC3 and in the glucose‐6‐phosphate transporter (G6PT/SLC37A4) are due to accumulation of 1,5‐anhydroglucitol‐6‐phosphate (1,5‐AG6P), an inhibitor of hexokinase made from 1,5‐anhydroglucitol (1,5‐AG), an abundant polyol present in bloo...

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Detalles Bibliográficos
Autores principales: Boulanger, Cécile, Stephenne, Xavier, Diederich, Jennifer, Mounkoro, Pierre, Chevalier, Nathalie, Ferster, Alina, Van Schaftingen, Emile, Veiga‐da‐Cunha, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540799/
https://www.ncbi.nlm.nih.gov/pubmed/35506446
http://dx.doi.org/10.1002/jimd.12509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540799/
https://www.ncbi.nlm.nih.gov/pubmed/35506446
http://dx.doi.org/10.1002/jimd.12509

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