Transferrin receptor 2 (Tfr2) genetic deletion makes transfusion‐independent a murine model of transfusion‐dependent β‐thalassemia

β‐thalassemia is a genetic disorder caused by mutations in the β‐globin gene, and characterized by anemia, ineffective erythropoiesis and iron overload. Patients affected by the most severe transfusion‐dependent form of the disease (TDT) require lifelong blood transfusions and iron chelation therapy...

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Detalles Bibliográficos
Autores principales: Di Modica, Simona Maria, Tanzi, Emanuele, Olivari, Violante, Lidonnici, Maria Rosa, Pettinato, Mariateresa, Pagani, Alessia, Tiboni, Francesca, Furiosi, Valeria, Silvestri, Laura, Ferrari, Giuliana, Rivella, Stefano, Nai, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540808/
https://www.ncbi.nlm.nih.gov/pubmed/36071579
http://dx.doi.org/10.1002/ajh.26673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540808/
https://www.ncbi.nlm.nih.gov/pubmed/36071579
http://dx.doi.org/10.1002/ajh.26673

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