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Dapagliflozin reduces uric acid concentration, an independent predictor of adverse outcomes in DAPA‐HF

AIMS: Blood uric acid (UA) levels are frequently elevated in patients with heart failure and reduced ejection fraction (HFrEF), may lead to gout and are associated with worse outcomes. Reduction in UA is desirable in HFrEF and sodium–glucose cotransporter 2 inhibitors may have this effect. We aimed...

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Detalles Bibliográficos
Autores principales: McDowell, Kirsty, Welsh, Paul, Docherty, Kieran F., Morrow, David A., Jhund, Pardeep S., de Boer, Rudolf A., O'Meara, Eileen, Inzucchi, Silvio E., Køber, Lars, Kosiborod, Mikhail N., Martinez, Felipe A., Ponikowski, Piotr, Hammarstedt, Ann, Langkilde, Anna Maria, Sjöstrand, Mikaela, Lindholm, Daniel, Solomon, Scott D., Sattar, Naveed, Sabatine, Marc S., McMurray, John J.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540869/
https://www.ncbi.nlm.nih.gov/pubmed/35064721
http://dx.doi.org/10.1002/ejhf.2433