First‐in‐Human Single‐Ascending‐Dose, Multiple‐Dose, and Food Interaction Studies of NRD.E1, an Innovative Nonopioid Therapy for Painful Diabetic Peripheral Neuropathy

Painful diabetic peripheral neuropathy is characterized by burning, stabbing, or electric shock–type pain, which severely impacts day‐to‐day functioning and quality of life. Here, we report the results of 3 phase I studies with NRD135S.E1 (referred to as NRD.E1), a new, orally available chemical ent...

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Detalles Bibliográficos
Autores principales: Tiecke, Eva, Rainisio, Maurizio, Guentert, Theodor, Müller, Stephan, Hochman, Liat, Kaplan, Eli, Mangialaio, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541015/
https://www.ncbi.nlm.nih.gov/pubmed/35699261
http://dx.doi.org/10.1002/cpdd.1103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541015/
https://www.ncbi.nlm.nih.gov/pubmed/35699261
http://dx.doi.org/10.1002/cpdd.1103

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