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NAD+ deficiency in human congenital malformations and miscarriage: A new model of pleiotropy
Pleiotropy is defined as the phenomenon of a single gene locus influencing two or more distinct phenotypic traits. However, nicotinamide adenine dinucleotide (NAD+) deficiency through diet alone can cause multiple or single malformations in mice. Additionally, humans with decreased NAD+ production d...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley & Sons, Inc.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541200/ https://www.ncbi.nlm.nih.gov/pubmed/35484986 http://dx.doi.org/10.1002/ajmg.a.62764 |