MITF deficiency and oncogenic GNAQ each promote proliferation programs in zebrafish melanocyte lineage cells

Uveal melanoma (UM) is the most common primary malignancy of the adult eye but lacks any FDA‐approved therapy for the deadly metastatic disease. Thus, there is a great need to dissect the driving mechanisms for UM and develop strategies to evaluate potential therapeutics. Using an autochthonous zebr...

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Detalles Bibliográficos
Autores principales: Phelps, Grace B., Amsterdam, Adam, Hagen, Hannah R., García, Nicole Zambrana, Lees, Jacqueline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541221/
https://www.ncbi.nlm.nih.gov/pubmed/35869673
http://dx.doi.org/10.1111/pcmr.13057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541221/
https://www.ncbi.nlm.nih.gov/pubmed/35869673
http://dx.doi.org/10.1111/pcmr.13057

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