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MITF deficiency and oncogenic GNAQ each promote proliferation programs in zebrafish melanocyte lineage cells
Uveal melanoma (UM) is the most common primary malignancy of the adult eye but lacks any FDA‐approved therapy for the deadly metastatic disease. Thus, there is a great need to dissect the driving mechanisms for UM and develop strategies to evaluate potential therapeutics. Using an autochthonous zebr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541221/ https://www.ncbi.nlm.nih.gov/pubmed/35869673 http://dx.doi.org/10.1111/pcmr.13057 |