Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport

The oncostatic effects of melatonin correlate with increased reactive oxygen species (ROS) levels, but how melatonin induces this ROS generation is unknown. In the present study, we aimed to elucidate the two seemingly opposing actions of melatonin regarding its relationship with free radicals. We a...

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Detalles Bibliográficos
Autores principales: Florido, Javier, Martinez‐Ruiz, Laura, Rodriguez‐Santana, César, López‐Rodríguez, Alba, Hidalgo‐Gutiérrez, Agustín, Cottet‐Rousselle, Cécile, Lamarche, Frédéric, Schlattner, Uwe, Guerra‐Librero, Ana, Aranda‐Martínez, Paula, Acuña‐Castroviejo, Darío, López, Luis C., Escames, Germaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541246/
https://www.ncbi.nlm.nih.gov/pubmed/35986493
http://dx.doi.org/10.1111/jpi.12824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541246/
https://www.ncbi.nlm.nih.gov/pubmed/35986493
http://dx.doi.org/10.1111/jpi.12824

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