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Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport
The oncostatic effects of melatonin correlate with increased reactive oxygen species (ROS) levels, but how melatonin induces this ROS generation is unknown. In the present study, we aimed to elucidate the two seemingly opposing actions of melatonin regarding its relationship with free radicals. We a...
Autores principales: | Florido, Javier, Martinez‐Ruiz, Laura, Rodriguez‐Santana, César, López‐Rodríguez, Alba, Hidalgo‐Gutiérrez, Agustín, Cottet‐Rousselle, Cécile, Lamarche, Frédéric, Schlattner, Uwe, Guerra‐Librero, Ana, Aranda‐Martínez, Paula, Acuña‐Castroviejo, Darío, López, Luis C., Escames, Germaine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541246/ https://www.ncbi.nlm.nih.gov/pubmed/35986493 http://dx.doi.org/10.1111/jpi.12824 |
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