Selective Oxidations Using a Cytochrome P450 Enzyme Variant Driven with Surrogate Oxygen Donors and Light

Cytochrome P450 monooxygenase enzymes are versatile catalysts, which have been adapted for multiple applications in chemical synthesis. Mutation of a highly conserved active site threonine to a glutamate can convert these enzymes into peroxygenases that utilise hydrogen peroxide (H(2)O(2)). Here, we...

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Detalles Bibliográficos
Autores principales: Lee, Joel H. Z., Podgorski, Matthew N., Moir, Michael, Gee, Alecia R., Bell, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541349/
https://www.ncbi.nlm.nih.gov/pubmed/35712785
http://dx.doi.org/10.1002/chem.202201366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541349/
https://www.ncbi.nlm.nih.gov/pubmed/35712785
http://dx.doi.org/10.1002/chem.202201366

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