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Selective Oxidations Using a Cytochrome P450 Enzyme Variant Driven with Surrogate Oxygen Donors and Light
Cytochrome P450 monooxygenase enzymes are versatile catalysts, which have been adapted for multiple applications in chemical synthesis. Mutation of a highly conserved active site threonine to a glutamate can convert these enzymes into peroxygenases that utilise hydrogen peroxide (H(2)O(2)). Here, we...
Autores principales: | Lee, Joel H. Z., Podgorski, Matthew N., Moir, Michael, Gee, Alecia R., Bell, Stephen G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541349/ https://www.ncbi.nlm.nih.gov/pubmed/35712785 http://dx.doi.org/10.1002/chem.202201366 |
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