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Potential role of regulatory DNA variants in modifying the risk of severe cutaneous reactions induced by aromatic anti‐seizure medications

OBJECTIVE: Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse drug reactions. Antiseizure medications (ASMs) with aromatic ring structure, including carbamazepine, are among the most common culprits. Screening for human leukocyte antigen (HLA) allele HLA...

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Detalles Bibliográficos
Autores principales: Mullan, Kerry A., Anderson, Alison, Shi, Yi‐Wu, Ding, Jia‐Hong, Ng, Ching‐Ching, Chen, Zhibin, Baum, Larry, Cherny, Stacey, Petrovski, Slave, Sham, Pak C., Lim, Kheng‐Seang, Liao, Wei‐Ping, Kwan, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541367/
https://www.ncbi.nlm.nih.gov/pubmed/35170024
http://dx.doi.org/10.1111/epi.17182