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Glucocorticoid receptor and androgen receptor-targeting therapy in patients with castration-resistant prostate cancer
OBJECTIVE: The glucocorticoid receptor (GR) promotes resistance to androgen receptor (AR)-targeting therapies in castration-resistant prostate cancer (CRPC) by bypassing AR blockade. However, the clinical relevance of evaluating GR expression in patients with CRPC has not been determined. The presen...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541428/ https://www.ncbi.nlm.nih.gov/pubmed/36212458 http://dx.doi.org/10.3389/fonc.2022.972572 |