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Glucocorticoid receptor and androgen receptor-targeting therapy in patients with castration-resistant prostate cancer

OBJECTIVE: The glucocorticoid receptor (GR) promotes resistance to androgen receptor (AR)-targeting therapies in castration-resistant prostate cancer (CRPC) by bypassing AR blockade. However, the clinical relevance of evaluating GR expression in patients with CRPC has not been determined. The presen...

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Detalles Bibliográficos
Autores principales: Pak, Sahyun, Suh, Jungyo, Park, Seo Young, Kim, Yunlim, Cho, Yong Mee, Ahn, Hanjong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541428/
https://www.ncbi.nlm.nih.gov/pubmed/36212458
http://dx.doi.org/10.3389/fonc.2022.972572