Exploring polygenic‐environment and residual‐environment interactions for depressive symptoms within the UK Biobank

Substantial advances have been made in identifying genetic contributions to depression, but little is known about how the effect of genes can be modulated by the environment, creating a gene–environment interaction. Using multivariate reaction norm models (MRNMs) within the UK Biobank (N = 61294–916...

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Detalles Bibliográficos
Autores principales: Gillett, Alexandra C., Jermy, Bradley S., Lee, Sang Hong, Pain, Oliver, Howard, David M., Hagenaars, Saskia P., Hanscombe, Ken B., Coleman, Jonathan R. I., Lewis, Cathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541465/
https://www.ncbi.nlm.nih.gov/pubmed/35438196
http://dx.doi.org/10.1002/gepi.22449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541465/
https://www.ncbi.nlm.nih.gov/pubmed/35438196
http://dx.doi.org/10.1002/gepi.22449

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