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Exploring polygenic‐environment and residual‐environment interactions for depressive symptoms within the UK Biobank
Substantial advances have been made in identifying genetic contributions to depression, but little is known about how the effect of genes can be modulated by the environment, creating a gene–environment interaction. Using multivariate reaction norm models (MRNMs) within the UK Biobank (N = 61294–916...
Autores principales: | Gillett, Alexandra C., Jermy, Bradley S., Lee, Sang Hong, Pain, Oliver, Howard, David M., Hagenaars, Saskia P., Hanscombe, Ken B., Coleman, Jonathan R. I., Lewis, Cathryn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541465/ https://www.ncbi.nlm.nih.gov/pubmed/35438196 http://dx.doi.org/10.1002/gepi.22449 |
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