Understanding the interaction of 14‐3‐3 proteins with hDMX and hDM2: a structural and biophysical study

p53 plays a critical role in regulating diverse biological processes: DNA repair, cell cycle arrest, apoptosis and senescence. The p53 pathway has therefore served as the focus of multiple drug‐discovery efforts. p53 is negatively regulated by hDMX and hDM2; prior studies have identified 14‐3‐3 prot...

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Detalles Bibliográficos
Autores principales: Srdanović, Sonja, Wolter, Madita, Trinh, Chi H., Ottmann, Christian, Warriner, Stuart L., Wilson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541495/
https://www.ncbi.nlm.nih.gov/pubmed/35286747
http://dx.doi.org/10.1111/febs.16433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541495/
https://www.ncbi.nlm.nih.gov/pubmed/35286747
http://dx.doi.org/10.1111/febs.16433

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