FAP(high) α‐SMA(low) cancer‐associated fibroblast‐derived SLPI protein encapsulated in extracellular vesicles promotes ovarian cancer development via activation of PI3K/AKT and downstream signaling pathways

Ovarian cancer is the most lethal gynecological malignancy worldwide with high metastasis and poor prognosis rates. Cancer‐associated fibroblasts (CAFs), a heterogeneous population of cells that constitutes a major component of the tumor microenvironment, secrete extracellular vesicles (EVs) loading...

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Detalles Bibliográficos
Autores principales: Sun, Luyao, Ke, Miaola, Wang, Xin, Yin, Mengyuan, Wei, Junni, Xu, Lu, Tian, Xing, Wang, Fei, Zhang, He, Fu, Songbin, Zhang, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541539/
https://www.ncbi.nlm.nih.gov/pubmed/35801406
http://dx.doi.org/10.1002/mc.23445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541539/
https://www.ncbi.nlm.nih.gov/pubmed/35801406
http://dx.doi.org/10.1002/mc.23445

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