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FAP(high) α‐SMA(low) cancer‐associated fibroblast‐derived SLPI protein encapsulated in extracellular vesicles promotes ovarian cancer development via activation of PI3K/AKT and downstream signaling pathways
Ovarian cancer is the most lethal gynecological malignancy worldwide with high metastasis and poor prognosis rates. Cancer‐associated fibroblasts (CAFs), a heterogeneous population of cells that constitutes a major component of the tumor microenvironment, secrete extracellular vesicles (EVs) loading...
Autores principales: | Sun, Luyao, Ke, Miaola, Wang, Xin, Yin, Mengyuan, Wei, Junni, Xu, Lu, Tian, Xing, Wang, Fei, Zhang, He, Fu, Songbin, Zhang, Chunyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541539/ https://www.ncbi.nlm.nih.gov/pubmed/35801406 http://dx.doi.org/10.1002/mc.23445 |
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