PlyAB Nanopores Detect Single Amino Acid Differences in Folded Haemoglobin from Blood

The real‐time identification of protein biomarkers is crucial for the development of point‐of‐care and portable devices. Here, we use a PlyAB biological nanopore to detect haemoglobin (Hb) variants. Adult haemoglobin (HbA) and sickle cell anaemia haemoglobin (HbS), which differ by just one amino aci...

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Detalles Bibliográficos
Autores principales: Huang, Gang, Voorspoels, Aderik, Versloot, Roderick Corstiaan Abraham, van der Heide, Nieck Jordy, Carlon, Enrico, Willems, Kherim, Maglia, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541544/
https://www.ncbi.nlm.nih.gov/pubmed/35759385
http://dx.doi.org/10.1002/anie.202206227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541544/
https://www.ncbi.nlm.nih.gov/pubmed/35759385
http://dx.doi.org/10.1002/anie.202206227

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