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PlyAB Nanopores Detect Single Amino Acid Differences in Folded Haemoglobin from Blood
The real‐time identification of protein biomarkers is crucial for the development of point‐of‐care and portable devices. Here, we use a PlyAB biological nanopore to detect haemoglobin (Hb) variants. Adult haemoglobin (HbA) and sickle cell anaemia haemoglobin (HbS), which differ by just one amino aci...
Autores principales: | Huang, Gang, Voorspoels, Aderik, Versloot, Roderick Corstiaan Abraham, van der Heide, Nieck Jordy, Carlon, Enrico, Willems, Kherim, Maglia, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541544/ https://www.ncbi.nlm.nih.gov/pubmed/35759385 http://dx.doi.org/10.1002/anie.202206227 |
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