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Disentangling the effects of traits with shared clustered genetic predictors using multivariable Mendelian randomization
When genetic variants in a gene cluster are associated with a disease outcome, the causal pathway from the variants to the outcome can be difficult to disentangle. For example, the chemokine receptor gene cluster contains genetic variants associated with various cytokines. Associations between varia...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541575/ https://www.ncbi.nlm.nih.gov/pubmed/35638254 http://dx.doi.org/10.1002/gepi.22462 |