Theacrine alleviates sepsis-induced acute kidney injury by repressing the activation of NLRP3/Caspase-1 inflammasome

Acute kidney injury (AKI) is a frequent and serious complication of sepsis, which results in a rapid decline of kidney function. Currently, there are no curative therapies for AKI. Theacrine is a purine alkaloid and exerts significant role in regulating inflammation, oxidative stress, and mood eleva...

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Detalles Bibliográficos
Autores principales: Yang, Maoxian, Shen, Peng, Xu, Longsheng, Kong, Min, Yu, Congcong, Shi, Yunchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541625/
https://www.ncbi.nlm.nih.gov/pubmed/36213494
http://dx.doi.org/10.7717/peerj.14109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541625/
https://www.ncbi.nlm.nih.gov/pubmed/36213494
http://dx.doi.org/10.7717/peerj.14109

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