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Theacrine alleviates sepsis-induced acute kidney injury by repressing the activation of NLRP3/Caspase-1 inflammasome
Acute kidney injury (AKI) is a frequent and serious complication of sepsis, which results in a rapid decline of kidney function. Currently, there are no curative therapies for AKI. Theacrine is a purine alkaloid and exerts significant role in regulating inflammation, oxidative stress, and mood eleva...
Autores principales: | Yang, Maoxian, Shen, Peng, Xu, Longsheng, Kong, Min, Yu, Congcong, Shi, Yunchao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541625/ https://www.ncbi.nlm.nih.gov/pubmed/36213494 http://dx.doi.org/10.7717/peerj.14109 |
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