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The highly expressed calcium‐insensitive synaptotagmin‐11 and synaptotagmin‐13 modulate insulin secretion

AIM: SYT11 and SYT13, two calcium‐insensitive synaptotagmins, are downregulated in islets from type 2 diabetic donors, but their function in insulin secretion is unknown. To address this, we investigated the physiological role of these two synaptotagmins in insulin‐secreting cells. METHODS: Correlat...

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Detalles Bibliográficos
Autores principales: Ofori, Jones K., Karagiannopoulos, Alexandros, Barghouth, Mohammad, Nagao, Mototsugu, Andersson, Markus E., Salunkhe, Vishal A., Zhang, Enming, Wendt, Anna, Eliasson, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541707/
https://www.ncbi.nlm.nih.gov/pubmed/35753051
http://dx.doi.org/10.1111/apha.13857